An Exonuclease I-Based Quencher-Free Fluorescent Method Using DNA Hairpin Probes for Rapid Detection of MicroRNA

An Exonuclease I-Based Quencher-Free Fluorescent Method Using DNA Hairpin Probes for Rapid Detection of MicroRNA

MicroRNAs (miRNAs) act as biomarkers for the diagnosis of a variety of cancers. Since the currently used methods for miRNA detection have limitations, simple, sensitive, and cost-effective methods for the detection of miRNA are required. This work demonstrates a facile, quencher-free, fluorescence-b...

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Bibliographic Details
Main Authors: Changbei Ma, Haisheng Liu, Kefeng Wu, Mingjian Chen, Liyang Zheng, Jun Wang
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Sensors
Subjects:
microRNA
quencher-free
exonuclease I
2-aminopurine
hairpin probe
Online Access:http://www.mdpi.com/1424-8220/17/4/760

Internet

http://www.mdpi.com/1424-8220/17/4/760

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