OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation
Abstract Breast cancer is the most common malignancy in women worldwide. Estrogen receptor α (ERα) is expressed in ∼70% of breast cancer cases and promotes estrogen-dependent cancer progression. In the present study, we identified OTU domain-containing 7B (OTUD7B), a deubiquitylase belonging to A20...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03785-7 |