OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation

Abstract Breast cancer is the most common malignancy in women worldwide. Estrogen receptor α (ERα) is expressed in ∼70% of breast cancer cases and promotes estrogen-dependent cancer progression. In the present study, we identified OTU domain-containing 7B (OTUD7B), a deubiquitylase belonging to A20...

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Bibliographic Details
Main Authors: Jianing Tang, Zeyu Wu, Zelin Tian, Wei Chen, Gaosong Wu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03785-7