Tumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell Leukemia

Tumor suppressor functions are essential to control cellular proliferation, to activate the apoptosis or senescence pathway to eliminate unwanted cells, to link DNA damage signals to cell cycle arrest checkpoints, to activate appropriate DNA repair pathways, and to prevent the loss of adhesion to in...

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Bibliographic Details
Main Author: Christophe Nicot
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2015/183590