N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin.

The gene product of SPINT 2, that encodes a transmembrane, Kunitz-type serine protease inhibitor independently designated as HAI-2 or placenta bikunin (PB), is involved in regulation of sodium absorption in human gastrointestinal track. Here, we show that SPINT 2 is expressed as two species of diffe...

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Bibliographic Details
Main Authors: Ying-Jung J Lai, Hsiang-Hua D Chang, Hongyu Lai, Yuan Xu, Frank Shiao, Nanxi Huang, Linpei Li, Ming-Shyue Lee, Michael D Johnson, Jehng-Kang Wang, Chen-Yong Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4501743?pdf=render