Modulation of Group I Ribozyme Activity by Cationic Porphyrins

The effects of cationic porphyrins on the catalytic activities of four group I ribozymes were investigated. A cationic porphyrin possessing four pyridinium moieties (pPyP) inhibited two group IC3 ribozymes (Syn Rz and Azo Rz) and a group IC1 ribozyme (Tet Rz). In the case of a group IA2 ribozyme (Td...

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Bibliographic Details
Main Authors: Shigeyoshi Matsumura, Tatsunobu Ito, Takahiro Tanaka, Hiroyuki Furuta, Yoshiya Ikawa
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Biology
Subjects:
RNA
Online Access:http://www.mdpi.com/2079-7737/4/2/251