Fast, potent pharmacological expansion of endogenous hes3+/sox2+ cells in the adult mouse and rat hippocampus.

The adult hippocampus is involved in learning and memory. As a consequence, it is a brain region of remarkable plasticity. This plasticity exhibits itself both as cellular changes and neurogenesis. For neurogenesis to occur, a population of local stem cells and progenitor cells is maintained in the...

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Bibliographic Details
Main Authors: Simone Pacioni, Maria Adele Rueger, Giuseppe Nisticò, Stefan R Bornstein, Deric M Park, Ron D McKay, Andreas Androutsellis-Theotokis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3518467?pdf=render