Prolyl Oligopeptidase From Leishmania infantum: Biochemical Characterization and Involvement in Macrophage Infection

Prolyl Oligopeptidase From Leishmania infantum: Biochemical Characterization and Involvement in Macrophage Infection

Leishmania infantum is a flagellated protozoan and one of the main causative agents of visceral leishmaniasis. This disease usually affects the human reticuloendothelial system, can cause death and available therapies may lead to serious side effects. Since it is a neglected tropical disease, the in...

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Bibliographic Details
Main Authors: Camila Lasse, Clênia S. Azevedo, Carla N. de Araújo, Flávia N. Motta, Milene A. Andrade, Amanda Pereira Rocha, Iracyara Sampaio, Sébastien Charneau, Marc Gèze, Philippe Grellier, Jaime M. Santana, Izabela M. D. Bastos
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
leishmaniasis
protease
POPLi
virulence factor
drug target
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01060/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01060/full

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