Ligation of MHC Class II Induces PKC-Dependent Clathrin-Mediated Endocytosis of MHC Class II

Ligation of MHC Class II Induces PKC-Dependent Clathrin-Mediated Endocytosis of MHC Class II

In addition to antigen presentation to CD4<sup>+</sup> T cells, aggregation of cell surface major histocompatibility complex class II (MHC-II) molecules induces signal transduction in antigen presenting cells that regulate cellular functions. We previously reported that crosslinking of M...

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Bibliographic Details
Main Authors: Kento Masaki, Yuhji Hiraki, Hiroka Onishi, Yuka Satoh, Paul A. Roche, Satoshi Tanaka, Kazuyuki Furuta
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
MHC-II
dendritic cells
endocytosis
crosslink
PKC
Online Access:https://www.mdpi.com/2073-4409/9/8/1810

Internet

https://www.mdpi.com/2073-4409/9/8/1810

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