Triiodothyronine increases mRNA and protein leptin levels in short time in 3T3-L1 adipocytes by PI3K pathway activation.

The present study aimed to examine the effects of thyroid hormone (TH), more precisely triiodothyronine (T3), on the modulation of leptin mRNA expression and the involvement of the phosphatidyl inositol 3 kinase (PI3K) signaling pathway in adipocytes, 3T3-L1, cell culture. We examined the involvemen...

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Bibliographic Details
Main Authors: Miriane de Oliveira, Renata de Azevedo Melo Luvizotto, Regiane Marques Castro Olimpio, Maria Teresa De Sibio, Sandro José Conde, Carolina Biz Rodrigues Silva, Fernanda Cristina Fontes Moretto, Célia Regina Nogueira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776751?pdf=render