Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.

Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.

Inflammatory bowel disease (IBD) is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but thought to result from a dysregulated adaptive and innate immune response to microbial products in a genetically susceptible host. Toll-like r...

Full description

Bibliographic Details
Main Authors:	Emily L Lowe, Timothy R Crother, Shervin Rabizadeh, Bing Hu, Hanlin Wang, Shuang Chen, Kenichi Shimada, Michelle H Wong, Kathrin S Michelsen, Moshe Arditi
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-09-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2946405?pdf=render

Similar Items

Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury
by: Nobuyuki Nosaka, et al.
Published: (2020-02-01)

Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis.
by: Antoine Soliman, et al.
Published: (2010-10-01)

Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection
by: Timothy R. Crother, et al.
Published: (2019-04-01)

Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection.
by: Kenichi Shimada, et al.
Published: (2011-01-01)

Plasmacytoid dendritic cells play a role for effective innate immune responses during Chlamydia pneumoniae infection in mice.
by: Timothy R Crother, et al.
Published: (2012-01-01)

Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells.
by: Timothy R Crother, et al.
Published: (2011-01-01)

Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis.
by: Madhulika Jupelli, et al.
Published: (2013-01-01)

Toll-like receptor-mediated responses of primary intestinal epithelial cells during the development of colitis
by: Singh, J.C.I., et al.
Published: (2009)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection
by: Kenichi Shimada, et al.
Published: (2009-04-01)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Lung Infection.
by: Kenichi Shimada, et al.
Published: (2009-04-01)

The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection.
by: Kenichi Shimada, et al.
Published: (2009-04-01)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Lung Infection.
by: Kenichi Shimada, et al.
Published: (2009-04-01)

Correction: The NOD/RIP2 Pathway Is Essential for Host Defenses Against Lung Infection.
by: Kenichi Shimada, et al.
Published: (2009-04-01)

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
by: Gantsetseg Tumurkhuu, et al.
Published: (2020-09-01)

The impact of Toll-like receptors on antigen presentation by mouse macrophages
by: Pupjain, Srijan
Published: (2008)

Transcript levels of Toll-Like receptors 5, 8 and 9 correlate with inflammatory activity in Ulcerative Colitis
by: Sánchez-Muñoz Fausto, et al.
Published: (2011-12-01)

Roles of Islet Toll-Like Receptors in Pig to Mouse Islet Xenotransplantation
by: Han Ro, et al.
Published: (2013-09-01)

Distinctive Recognition of Flagellin by Human and Mouse Toll-Like Receptor 5.
by: Vida Forstnerič, et al.
Published: (2016-01-01)

Piperlongumine Alleviates Mouse Colitis and Colitis-Associated Colorectal Cancer
by: Jia-Rong Huang, et al.
Published: (2020-11-01)

MD-2 as a possible therapeutic target for atherosclerosis
by: Shuang Chen, et al.
Published: (2020-05-01)

Expression of Toll-like receptors (TLRs) in the lungs of an experimental sepsis mouse model.
by: Anargyros Bakopoulos, et al.
Published: (2017-01-01)

Toll-Interacting Protein Regulates Immune Cell Infiltration and Promotes Colitis-Associated Cancer
by: Christina Begka, et al.
Published: (2020-03-01)

Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4.
by: Markus M Heimesaat, et al.
Published: (2007-07-01)

Toll-Like Receptor 4 Signaling Integrates Intestinal Inflammation with Tumorigenesis: Lessons from the Murine Model of Colitis-Associated Cancer
by: John Sotolongo, et al.
Published: (2011-08-01)

Effect of Pingchuan Formula on Toll-Like Receptors and Dendritic Cells in an Asthmatic Mouse Model
by: Fei Liu, et al.
Published: (2020-01-01)

Efficient of Toll‐Like Receptor 4 Knockout in Mouse Zygotes by CRISPER/Cas9
by: Delsuz Rezaee, et al.
Published: (2021-08-01)

Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.
by: Heather D Jones, et al.
Published: (2015-01-01)

Correction: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.
by: Heather D Jones, et al.
Published: (2015-01-01)

Toll-Like Receptors
by: Aycan Kundakcı, et al.
Published: (2012-08-01)

Toll-like Receptors
Published: (2020)

Mesenchymal stem cell transplantation improves chronic colitis-associated complications through inhibiting the activity of toll-like receptor-4 in mice
by: Guo chao Niu, et al.
Published: (2018-08-01)

Toll-Like Receptors in Hepatic Ischemia/Reperfusion and Transplantation
by: John Evankovich, et al.
Published: (2010-01-01)

The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome
by: Carlene Petes, et al.
Published: (2017-09-01)

Toll-Like Receptor Signaling in Liver Diseases
by: Gyongyi Szabo, et al.
Published: (2010-01-01)

The Absence of Toll-Like Receptor 4 Mildly Affects the Structure and Function in the Adult Mouse Retina
by: Agustina Noailles, et al.
Published: (2019-02-01)

Role of Toll-like receptor 9 in mouse lung inflammation in response to chicken barn air
by: Schneberger, David
Published: (2011)

Role of the innate immune response and toll-like receptors following spinal cord injury in the mouse
by: Kigerl, Kristina Ann
Published: (2006)

Toll-like receptor-4, but not toll-like receptor-2 mediates secretion of tumour necrosis factor α and interleukin-8 in lipopolysaccharide-stimulated mouse mammary epithelial cells
by: He Chang-Liang, et al.
Published: (2013-09-01)

Structural insights into the exclusive adaptors of Toll-like Receptor 4 signalling
by: Wong, Joyce
Published: (2008)

Affective state determination in a mouse model of colitis-associated colorectal cancer.
by: Lauren C Chartier, et al.
Published: (2020-01-01)

Cannot write session to /tmp/vufind_sessions/sess_kminv11reshkgkb77oc2p9kgek