Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.
Inflammatory bowel disease (IBD) is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but thought to result from a dysregulated adaptive and innate immune response to microbial products in a genetically susceptible host. Toll-like r...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2946405?pdf=render |