Prioritizing second-generation SARS-CoV-2 vaccines through low-dosage challenge studies

Prioritizing second-generation SARS-CoV-2 vaccines through low-dosage challenge studies

The design of human challenge studies balances scientific validity, efficiency and study safety. This Perspective explores some advantages and disadvantages of ‘low-dosage’ challenge studies, in the setting of testing second-generation vaccines against COVID-19. Compared with a conventional vaccine...

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Bibliographic Details
Main Authors: Bastian Steuwer, Euzebiusz Jamrozik, Nir Eyal
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:International Journal of Infectious Diseases
Subjects:
Coronavirus
Vaccines
Human challenge studies
Research design
Ethics
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221001247

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http://www.sciencedirect.com/science/article/pii/S1201971221001247

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