Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses
While T cells recognise the complex of peptide and major histocompatibility complex (MHC) at the cell surface, changes in the dose and/or structure of the peptide component can have profound effects on T cell activation and function. In addition, the repertoire of T cells capable of responding to an...
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Format: | Article |
Language: | English |
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MDPI AG
2014-07-01
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Series: | Vaccines |
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Online Access: | http://www.mdpi.com/2076-393X/2/3/537 |