PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells

The double-stranded RNA-activated protein kinase R (PKR) is a Type I interferon (IFN) stimulated gene that has important biological and immunological functions. In viral infections, in general, PKR inhibits or promotes viral replication, but PKR-IPNV interaction has not been previously studied. We i...

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Bibliographic Details
Main Authors: Amr A.A. Gamil, Cheng Xu, Stephen Mutoloki, Øystein Evensen
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Viruses
Subjects:
PKR
Online Access:http://www.mdpi.com/1999-4915/8/6/173