The combination of asymmetric hydrogenation of olefins and direct reductive amination

Asymmetric hydrogenation (AH) and direct reductive amination (DRA) are both frequently utilized in chemical industry. Here, the authors combine these two transformations to efficiently convert in one step prochiral olefins into chiral amino compounds.

Bibliographic Details
Main Authors: Shuai Yuan, Guorui Gao, Lili Wang, Cungang Liu, Lei Wan, Haizhou Huang, Huiling Geng, Mingxin Chang
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14475-x