EMQIT: a machine learning approach for energy based PWM matrix quality improvement
Abstract Background Transcription factor binding affinities to DNA play a key role for the gene regulation. Learning the specificity of the mechanisms of binding TFs to DNA is important both to experimentalists and theoreticians. With the development of high-throughput methods such as, e.g., ChiP-se...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-08-01
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| Series: | Biology Direct |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13062-017-0189-y |