Impaired angiogenesis during fracture healing in GPCR kinase 2 interacting protein-1 (GIT1) knock out mice.

G protein coupled receptor kinase 2 (GRK2) interacting protein-1 (GIT1), is a scaffold protein that plays an important role in angiogenesis and osteoclast activity. We have previously demonstrated that GIT1 knockout (GIT1 KO) mice have impaired angiogenesis and dysregulated osteoclast podosome forma...

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Bibliographic Details
Main Authors: Guoyong Yin, Tzong-Jen Sheu, Prashanthi Menon, Jinjiang Pang, Hsin-Chiu Ho, Shanshan Shi, Chao Xie, Elaine Smolock, Chen Yan, Michael J Zuscik, Bradford C Berk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3929643?pdf=render