Succinylated whey protein isolate as a sustained-release excipient of puerarin derivative oral tablets: Preparation, optimization and pharmacokinetics

This work was done to investigate succinylated commercial whey protein isolate (S-WPI) as an oral sustained-release delivery carrier for puerarin 5 (PR-5). The succinylation conditions were established for S-WPIs by optimization of single factor study and Box–Beehnken design. The effect of succinyla...

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Bibliographic Details
Main Authors: Rui Zhang, Yu Zhang, Yue Wu, Jun Liu, Tiantian Ye, Shujun Wang
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Asian Journal of Pharmaceutical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087618302034