Angiotensin II infusion induces marked diaphragmatic skeletal muscle atrophy.

Advanced congestive heart failure (CHF) and chronic kidney disease (CKD) are characterized by increased angiotensin II (Ang II) levels and are often accompanied by significant skeletal muscle wasting that negatively impacts mortality and morbidity. Both CHF and CKD patients have respiratory muscle d...

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Bibliographic Details
Main Authors: Bashir M Rezk, Tadashi Yoshida, Laura Semprun-Prieto, Yusuke Higashi, Sergiy Sukhanov, Patrice Delafontaine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3262800?pdf=render