Treatment of bipolar depression with supraphysiologic doses of levothyroxine: a randomized, placebo-controlled study of comorbid anxiety symptoms

Abstract Background Symptoms of anxiety co-occur in a variety of disorders including in depressive episodes of bipolar disorder and in patients with thyrotoxicosis. Treatment of refractory bipolar disorder with supraphysiologic doses of levothyroxine (L-T4) has been shown to improve the phenotypic e...

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Bibliographic Details
Main Authors: Maximilian Pilhatsch, Thomas J Stamm, Petra Stahl, Ute Lewitzka, Anne Berghöfer, Cathrin Sauer, Michael Gitlin, Mark A. Frye, Peter C. Whybrow, Michael Bauer
Format: Article
Language:English
Published: SpringerOpen 2019-10-01
Series:International Journal of Bipolar Disorders
Online Access:http://link.springer.com/article/10.1186/s40345-019-0155-y