Aromatic Hydrocarbon Receptor Suppresses Prostate Cancer Bone Metastasis Cells-Induced Vasculogenesis of Endothelial Progenitor Cells under Hypoxia

Aromatic Hydrocarbon Receptor Suppresses Prostate Cancer Bone Metastasis Cells-Induced Vasculogenesis of Endothelial Progenitor Cells under Hypoxia

Background/Aims: Hypoxia leads to the development of neovascularization in solid tumor by regulating VEGF expression. Aromatic hydrocarbon receptor (AHR), a receptor for dioxin-like compounds, functions as a transcription factor through dimerization with hypoxia-inducible factors 1β (HIF-1β) and inh...

Full description

Bibliographic Details
Main Authors: Shuai Huang, Yuanqing Guo, Angela Jacobi, Ziqing Li, Sheng Huang, Jianan He, Xingmo Liu, Yubo Tang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Bone metastasis
EPCs
Hypoxia
Vasculogenesis
Aromatic hydrocarbon receptor
Online Access:http://www.karger.com/Article/FullText/445662

Internet

http://www.karger.com/Article/FullText/445662

Similar Items