Genetic variants in ATM, H2AFX and MRE11 genes and susceptibility to breast cancer in the polish population

Genetic variants in ATM, H2AFX and MRE11 genes and susceptibility to breast cancer in the polish population

Abstract Background DNA damage repair is a complex process, which can trigger the development of cancer if disturbed. In this study, we hypothesize a role of variants in the ATM, H2AFX and MRE11 genes in determining breast cancer (BC) susceptibility. Methods We examined the whole sequence of the ATM...

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Bibliographic Details
Main Authors: Marta Podralska, Iwona Ziółkowska-Suchanek, Magdalena Żurawek, Agnieszka Dzikiewicz-Krawczyk, Ryszard Słomski, Jerzy Nowak, Agnieszka Stembalska, Karolina Pesz, Maria Mosor
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
ATM
H2AFX
MRE11
DNA repair
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4360-3

Internet

http://link.springer.com/article/10.1186/s12885-018-4360-3

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