Method Specific Calibration Corrects for DNA Extraction Method Effects on Relative Telomere Length Measurements by Quantitative PCR.

Telomere length (TL) is increasingly being used as a biomarker in epidemiological, biomedical and ecological studies. A wide range of DNA extraction techniques have been used in telomere experiments and recent quantitative PCR (qPCR) based studies suggest that the choice of DNA extraction method may...

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Bibliographic Details
Main Authors: Luise A Seeker, Rebecca Holland, Sarah Underwood, Jennifer Fairlie, Androniki Psifidi, Joanna J Ilska, Ainsley Bagnall, Bruce Whitelaw, Mike Coffey, Georgios Banos, Daniel H Nussey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5056729?pdf=render