Depression-like effect of prenatal buprenorphine exposure in rats.

Studies indicate that perinatal opioid exposure produces a variety of short- and long-term neurobehavioral consequences. However, the precise modes of action are incompletely understood. Buprenorphine, a mixed agonist/antagonist at the opioid receptors, is currently being used in clinical trials for...

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Bibliographic Details
Main Authors: Chih-Jen Hung, Chih-Cheng Wu, Wen-Ying Chen, Cheng-Yi Chang, Yu-Hsiang Kuan, Hung-Chuan Pan, Su-Lan Liao, Chun-Jung Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867331?pdf=render