Low mitochondrial DNA copy number of resected cecum appendix correlates with high severity of acute appendicitis

Low mitochondrial DNA copy number of resected cecum appendix correlates with high severity of acute appendicitis

Background/Purpose: The roles of mitochondrial DNA alterations in acute appendicitis (AA) remain unclear. We evaluated the alterations of mtDNA copy number and mtDNA integrity [proportion of mtDNA templates without 8-hydroxyl-2′-deoxyguanosine (8-OHdG)] of the resected cecum appendixes in clinically...

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Bibliographic Details
Main Authors: Wei-Cheng Lee, Chen-Sung Lin, Fang-Chu Ko, Wei Cheng, Mau-Hwa Lee, Yau-Huei Wei
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of the Formosan Medical Association
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664618300731

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