Low mitochondrial DNA copy number of resected cecum appendix correlates with high severity of acute appendicitis

Background/Purpose: The roles of mitochondrial DNA alterations in acute appendicitis (AA) remain unclear. We evaluated the alterations of mtDNA copy number and mtDNA integrity [proportion of mtDNA templates without 8-hydroxyl-2′-deoxyguanosine (8-OHdG)] of the resected cecum appendixes in clinically...

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Bibliographic Details
Main Authors: Wei-Cheng Lee, Chen-Sung Lin, Fang-Chu Ko, Wei Cheng, Mau-Hwa Lee, Yau-Huei Wei
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of the Formosan Medical Association
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664618300731