MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

Gene dosage effects of Amyloid precursor protein (APP) can cause familial AD. Recent evidence suggest that microRNA (miRNA) pathways, implicated in gene transcriptional control, could be involved in the development of sporadic Alzheimer's disease (AD). We therefore investigated whether miRNAs c...

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Bibliographic Details
Main Authors: Sébastien S. Hébert, Katrien Horré, Laura Nicolaï, Bruno Bergmans, Aikaterini S. Papadopoulou, André Delacourte, Bart De Strooper
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Neurobiology of Disease
Subjects:
MicroRNA
Non-coding RNA
Amyloid precursor protein
Alzheimer's disease
Gene transcription
Secretase
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002982

Internet

http://www.sciencedirect.com/science/article/pii/S0969996108002982

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