Effect of sedation with dexmedetomidine or propofol on gastrointestinal motility in lipopolysaccharide-induced endotoxemic mice

Abstract Background Sepsis often accompanies gastrointestinal motility disorder that contributes to the development of sepsis in turn. Propofol and dexmedetomidine, as widely used sedatives in patients with sepsis, are likely to depress gastrointestinal peristalsis. We queried whether propofol or de...

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Bibliographic Details
Main Authors: Haiqing Chang, Shuang Li, Yansong Li, Hao Hu, Bo Cheng, Jiwen Miao, Hui Gao, Hongli Ma, Yanfeng Gao, Qiang Wang
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Anesthesiology
Subjects:
ICU
Online Access:http://link.springer.com/article/10.1186/s12871-020-01146-z