Modulation of phenylalanine and tyrosine concentrations by ischemia and guanosine in neuronal PC12 cells

Survival of neurons is dependent on the presence of trophic and non-trophic factors. We have previously observed the protective capacity of purine nucleosides in hypoxic neuronal cell cultures. Guanosine appeared especially interesting with respect to its remarkable neurite-stimulating aptitude. Her...

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Bibliographic Details
Main Authors: Thauerer Bettina, Geisler Simon, Fuchs Dietmar, Baier-Bitterlich Gabriele
Format: Article
Language:English
Published: De Gruyter 2013-12-01
Series:Pteridines
Subjects:
Online Access:https://doi.org/10.1515/pterid-2013-0036