A deep learning approach to programmable RNA switches

RNA can be used as a programmable tool for detection of biological analytes. Here the authors use deep neural networks to predict toehold switch functionality in synthetic biology applications.

Bibliographic Details
Main Authors: Nicolaas M. Angenent-Mari, Alexander S. Garruss, Luis R. Soenksen, George Church, James J. Collins
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18677-1