The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans.

Glutathione (GSH) and GSH-dependent enzymes play a key role in cellular detoxification processes that enable organism to cope with various internal and environmental stressors. However, it is often not clear, which components of the complex GSH-metabolism are required for tolerance towards a certain...

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Bibliographic Details
Main Authors: Kai Lüersen, Dirk Stegehake, Jens Daniel, Mike Drescher, Irene Ajonina, Caroline Ajonina, Patrick Hertel, Christian Woltersdorf, Eva Liebau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620388?pdf=render