Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury

Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury

<p>Abstract</p> <p>Background</p> <p>Stimulation of epithelial sodium channel (ENaC) increases Na<sup>+ </sup>transport, a driving force of alveolar fluid clearance (AFC) to keep alveolar spaces free of edema fluid that is beneficial for acute lung injury (A...

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Bibliographic Details
Main Authors: Deng Wang, Li Chang-Yi, Tong Jin, Zhang Wei, Wang Dao-Xin
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Respiratory Research
Subjects:
Alveolar fluid clearance
Akt
Epithelial sodium channel
Insulin
Phosphatidylinositol 3-kinase
Acute lung injury
Online Access:http://respiratory-research.com/content/13/1/29

Internet

http://respiratory-research.com/content/13/1/29

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