Cu(II) and Ni(II) Interactions with the Terminally Blocked Hexapeptide Ac-Leu-Ala-His-Tyr-Asn-Lys-amide Model of Histone H2B (80–85)

The N- and C-terminal blocked hexapeptide Ac-Leu-Ala-His-Tyr-Asn-Lys-amide (LAHYNK) representing the 80–85 fragment of histone H2B was synthesized and its interactions with Cu(II) and Ni(II) ions were studied by potentiometric, UV-Vis, CD, EPR, and NMR spectroscopic techniques in solution. Our data...

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Bibliographic Details
Main Authors: Katerina Panagiotou, Maria Panagopoulou, Tilemachos Karavelas, Vassiliki Dokorou, Andrew Hagarman, Jonathan Soffer, Reinhard Schweitzer-Stenner, Gerasimos Malandrinos, Nick Hadjiliadis
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2008/257038