Daratumumab for Treatment of Antibody-Mediated Rejection after ABO-Incompatible Kidney Transplantation

We report the effectiveness of daratumumab, a human IgGκ monoclonal antibody targeting CD38 on plasma cells, for therapy-refractory antibody-mediated rejection (AMR) due to blood group antibodies in a 59-year-old man who received a living ABO-incompatible kidney transplantation. Standard treatment o...

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Bibliographic Details
Main Authors: Davide Spica, Till Junker, Michael Dickenmann, Stefan Schaub, Jürg Steiger, Tanja Rüfli, Jörg Halter, Helmut Hopfer, Andreas Holbro, Patricia Hirt-Minkowski
Format: Article
Language:English
Published: Karger Publishers 2019-11-01
Series:Case Reports in Nephrology and Dialysis
Subjects:
Online Access:https://www.karger.com/Article/FullText/503951