The role of sperm associated antigen 6 gene in morphological changes of inner ear development and signal regulation of auditory organs in mice

Aim: In order to analyze the effects of the deletion of the Sperm Associated Antigen 6 (Spag6) gene on the inner ear and the auditory system of mice. Method: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology was utilized, and the Spag6 gene knockout mouse model was c...

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Bibliographic Details
Main Authors: He Li, Jun Lv, Qinshuang Zhou, Lanlan Jin, Zonghui Kang, Yideng Huang
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of King Saud University: Science
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364719318816