Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection

Kinase activity plays an essential role in the regulation of immune cell defenses against pathogens. The protein kinase CK2 (formerly casein kinase II) is an evolutionarily conserved kinase with hundreds of identified substrates. CK2 is ubiquitously expressed in somatic and immune cells, but the rol...

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Bibliographic Details
Main Authors: Sandy R. Larson, Nikki Bortell, Alysha Illies, William J. Crisler, Jennifer L. Matsuda, Laurel L. Lenz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
CK2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.590266/full