Immune Complex-Induced, Nitric Oxide-Mediated Vascular Endothelial Cell Death by Phagocytes Is Prevented with Decoy FcγReceptors.

Immune Complex-Induced, Nitric Oxide-Mediated Vascular Endothelial Cell Death by Phagocytes Is Prevented with Decoy FcγReceptors.

Autoimmune vasculitis is an endothelial inflammatory disease that results from the deposition of immune-complexes (ICs) in blood vessels. The interaction between Fcgamma receptors (FcγRs) expressed on inflammatory cells with ICs is known to cause blood vessel damage. Hence, blocking the interaction...

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Bibliographic Details
Main Authors: Ramanjaneya V R Mula, Deepa Machiah, Lauren Holland, Xinyu Wang, Harish Parihar, Avadhesh C Sharma, Periasamy Selvaraj, Rangaiah Shashidharamurthy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4839578?pdf=render

Internet

http://europepmc.org/articles/PMC4839578?pdf=render

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