Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D<sub>1</sub> and D<sub>2</sub> Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening

Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D<sub>1</sub> and D<sub>2</sub> Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening

Adenylyl cyclase type 5 (AC5), as the principal isoform expressed in striatal medium spiny neurons (MSNs), is essential for the integration of both stimulatory and inhibitory midbrain signals that initiate from dopaminergic G protein-coupled receptor (GPCR) activation. The spatial and temporal contr...

Full description

Bibliographic Details
Main Authors: Trevor B. Doyle, Brian S. Muntean, Karin F. Ejendal, Michael P. Hayes, Monica Soto-Velasquez, Kirill A. Martemyanov, Carmen W. Dessauer, Chang-Deng Hu, Val J. Watts
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
adenylyl cyclase
ac5
bifc
camp
dopamine
pp2a
striatum
napa
Online Access:https://www.mdpi.com/2073-4409/8/11/1468

Internet

https://www.mdpi.com/2073-4409/8/11/1468

Similar Items