HIV-1-derived exosomal microRNAs miR88 and miR99 promote the release of cytokines from human alveolar macrophages by binding to TLR8

The human monocytic cell line U937 and human alveolar macrophages were used as in vitro models to explore the role of miR88 and miR99 in the chronic abnormal activation of the body caused by human immunodeficiency virus (HIV). The functions and underlying mechanisms of miR88 and miR99 were studied b...

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Bibliographic Details
Main Authors: Hui Zhao, Zhenming Sun, Lifang Li, Shuyin Zhi, Yiru Zhao, Zhihua Zhang, Runyu Wang, Jianqiang Li
Format: Article
Language:English
Published: SAGE Publishing 2019-08-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/2058739219870434