Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

Objective: Hepatocyte deletion of estrogen receptor alpha (LKO-ERα) worsens fatty liver, dyslipidemia, and insulin resistance in high-fat diet fed female mice. However, whether or not hepatocyte ERα regulates reverse cholesterol transport (RCT) in mice has not yet been reported. Methods and results:...

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Bibliographic Details
Main Authors: Lin Zhu, Jeanne Shi, Thao N. Luu, Joshua C. Neuman, Elijah Trefts, Sophia Yu, Brian T. Palmisano, David H. Wasserman, MacRae F. Linton, John M. Stafford
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781730683X

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http://www.sciencedirect.com/science/article/pii/S221287781730683X

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