Oligomerization of a molecular chaperone modulates its activity

Oligomerization of a molecular chaperone modulates its activity

Molecular chaperones alter the folding properties of cellular proteins via mechanisms that are not well understood. Here, we show that Trigger Factor (TF), an ATP-independent chaperone, exerts strikingly contrasting effects on the folding of non-native proteins as it transitions between a monomeric...

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Bibliographic Details
Main Authors: Tomohide Saio, Soichiro Kawagoe, Koichiro Ishimori, Charalampos G Kalodimos
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
molecular chaperones
protein folding
NMR Spectroscopy
Online Access:https://elifesciences.org/articles/35731

Internet

https://elifesciences.org/articles/35731

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