Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans.

<h4>Background</h4>HIV vaccine trials routinely measure multiple vaccine-elicited immune responses to compare regimens and study their potential associations with protection. Here we employ unsupervised learning tools facilitated by a bidirectional power transformation to explore the mul...

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Bibliographic Details
Main Authors: Lue Ping Zhao, Andrew Fiore-Gartland, Lindsay N Carpp, Kristen W Cohen, Nadine Rouphael, Llewellyn Fleurs, One Dintwe, Michael Zhao, Zoe Moodie, Youyi Fong, Nigel Garrett, Ying Huang, Craig Innes, Holly E Janes, Erica Lazarus, Nelson L Michael, Sorachai Nitayaphan, Punnee Pitisuttithum, Supachai Rerks-Ngarm, Merlin L Robb, Stephen C De Rosa, Lawrence Corey, Glenda E Gray, Kelly E Seaton, Nicole L Yates, M Juliana McElrath, Nicole Frahm, Georgia D Tomaras, Peter B Gilbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226803