Development and aging of the Kisspeptin-GPR54 system in the mammalian brain: what are the impacts on female reproductive function?

The prominent role of the G protein coupled receptor GPR54 and its peptide ligand kisspeptin in the progression of puberty has been extensively documented in many mammalian species including humans. Kisspeptins are very potent GnRH secretagogues produced by two main populations of neurons located in...

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Bibliographic Details
Main Authors: Isabelle eFranceschini, Elodie eDesroziers
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00022/full