Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway

Parisa Momtaz,1,2 Michael A Postow1,2 1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; 2Weill Cornell Medical College, New York, NY, USA Abstract: T-lymphocytes have the potential to recognize cancer antigens as foreign and therefore eliminate them. However, immu...

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Bibliographic Details
Main Authors: Momtaz P, Postow MA
Format: Article
Language:English
Published: Dove Medical Press 2014-11-01
Series:Pharmacogenomics and Personalized Medicine
Online Access:http://www.dovepress.com/immunologic-checkpoints-in-cancer-therapy-focus-on-the-programmed-deat-peer-reviewed-article-PGPM