Effect of Donepezil on Group II mGlu Receptor Agonist- or Antagonist-Induced Amnesia on Passive Avoidance in Mice

We examined the effect of the acetylcholinesterase (ACHE) inhibitor, donepezil hydrocloride (DONP), on group II metabotropic glutamate (mGlu) receptor agonist- or antagonist-induced amnesia in the step-through passive avoidance task in male mice. DCG-IV, a group II mGlu receptor agonist, at dose of...

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Bibliographic Details
Main Authors: Tomoaki Sato, Koh-ichi Tanaka, Yoshiko Ohnishi, Masahiro Irifune, Takashige Nishikawa
Format: Article
Language:English
Published: Hindawi Limited 2003-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/NP.2003.319