The use of high-resolution melting techniques for mutation screening of diseases caused by trinucleotide repeats expansion, with emphasis on the <em> AR </em> gene

The use of high-resolution melting techniques for mutation screening of diseases caused by trinucleotide repeats expansion, with emphasis on the <em> AR </em> gene

BACKGROUND Trinucleotide repeat expansion (TRE) diseases are genetic diseases caused by an increase in the number of CAG, CGG, and CTG codons. CAG repeat expansion in exon 1 of the androgen receptor (AR) gene is known to be associated with disorders of sex development (DSD) and spinal and bulbar mu...

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Bibliographic Details
Main Authors: Achmad Zulfa Juniarto, Mahayu Dewi Ariani, Stefani Harumsari, Nurin Aisyiyah Listyasari, Hardian, Agustini Utari, Sultana Muhammad Hussein Faradz
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2019-08-01
Series:Medical Journal of Indonesia
Subjects:
androgen receptor
disorders of sex development
genetic screening
hypospadias
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/3008

Internet

http://mji.ui.ac.id/journal/index.php/mji/article/view/3008

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