A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells

A robust Pax7EGFP mouse that enables the visualization of dynamic behaviors of muscle stem cells

Abstract Background Pax7 is a transcription factor involved in the specification and maintenance of muscle stem cells (MuSCs). Upon injury, MuSCs leave their quiescent state, downregulate Pax7 and differentiate, contributing to skeletal muscle regeneration. In the majority of regeneration studies, M...

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Bibliographic Details
Main Authors: Elisia D. Tichy, David K. Sidibe, Christopher D. Greer, Nicholas M. Oyster, Panteleimon Rompolas, Nadia A. Rosenthal, Helen M. Blau, Foteini Mourkioti
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Skeletal Muscle
Subjects:
Skeletal muscle
Pax7
EGFP
Muscle stem cell
Satellite cell
Muscle development
Online Access:http://link.springer.com/article/10.1186/s13395-018-0169-7

Internet

http://link.springer.com/article/10.1186/s13395-018-0169-7

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