Reciprocal interactions between osteoclasts and nociceptive sensory neurons in bone cancer pain

Abstract. Many common cancers such as breast, prostate, and lung cancer metastasize to bones at advanced stages, producing severe pain and functional impairment. At present, the current pharmacotherapies available for bone cancer pain are insufficient to provide safe and efficacious pain relief. In...

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Bibliographic Details
Main Authors: Amanda S. Andriessen, Christopher R. Donnelly, Ru-Rong Ji
Format: Article
Language:English
Published: Wolters Kluwer 2021-01-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000867