The transcription factor MafB promotes anti-inflammatory M2 polarization and cholesterol efflux in macrophages

Abstract Macrophages play pivotal roles in the progression and regression of atherosclerosis. Accumulating evidence suggests that macrophage polarization into an anti-inflammatory M2 state is a key characteristic of atherosclerotic plaques undergoing regression. However, the molecular mechanisms und...

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Bibliographic Details
Main Author: Hwijin Kim
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07381-8