Colorectal Cancer: Genetic Abnormalities, Tumor Progression, Tumor Heterogeneity, Clonal Evolution and Tumor-Initiating Cells

Colon cancer is the third most common cancer worldwide. Most colorectal cancer occurrences are sporadic, not related to genetic predisposition or family history; however, 20–30% of patients with colorectal cancer have a family history of colorectal cancer and 5% of these tumors arise in th...

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Bibliographic Details
Main Authors: Ugo Testa, Elvira Pelosi, Germana Castelli
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Medical Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3271/6/2/31